Retinoblastoma-repression of E2F-dependent transcription depends on the ability of the retinoblastoma protein to interact with E2F and is abrogated by the adenovirus E1A oncoprotein.

Ítems similars

• Phosphorylation-dependent activation of the adenovirus-inducible E2F transcription factor in a cell-free system.
  per: Bagchi, S, et al.
  Publicat: (1989)
• Adenovirus E1a prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor.
  per: Zamanian, M, et al.
  Publicat: (1992)
• The adenovirus-inducible factor E2F stimulates transcription after specific DNA binding.
  per: Yee, A S, et al.
  Publicat: (1989)
• The human papillomavirus E7 oncoprotein and the cellular transcription factor E2F bind to separate sites on the retinoblastoma tumor suppressor protein.
  per: Wu, E W, et al.
  Publicat: (1993)
• Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors
  per: Toki, Hideaki, et al.
  Publicat: (2014)