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Adenovirus E1a prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor.

The retinoblastoma (Rb) gene product forms a complex with the cellular transcription factor DRTF1, a property assumed to be important for mediating negative growth control because certain viral oncogenes, such as adenovirus E1a, prevent this interaction and mutant Rb alleles, which have lost the cap...

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Bibliografski detalji
Glavni autori: Zamanian, M, La Thangue, N B
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC556735/
https://ncbi.nlm.nih.gov/pubmed/1385776
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