Loading...
Novel retinoblastoma mutation abrogating the interaction to E2F2/3, but not E2F1, led to selective suppression of thyroid tumors
Mutant mouse models are indispensable tools for clarifying gene functions and elucidating the pathogenic mechanisms of human diseases. Here, we describe novel cancer models bearing point mutations in the retinoblastoma gene (Rb1) generated by N-ethyl-N-nitrosourea mutagenesis. Two mutations in splic...
Na minha lista:
| Udgivet i: | Cancer Sci |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2014
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4462357/ https://ncbi.nlm.nih.gov/pubmed/25088905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12495 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|