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Identification of Reliable Components in Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS): a Data-Driven Approach across Metabolic Processes

There is an increasing need to use multivariate statistical methods for understanding biological functions, identifying the mechanisms of diseases, and exploring biomarkers. In addition to classical analyses such as hierarchical cluster analysis, principal component analysis, and partial least squar...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Motegi, Hiromi, Tsuboi, Yuuri, Saga, Ayako, Kagami, Tomoko, Inoue, Maki, Toki, Hideaki, Minowa, Osamu, Noda, Tetsuo, Kikuchi, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632111/
https://ncbi.nlm.nih.gov/pubmed/26531245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15710
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