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A Combinatorial Mechanism for Determining the Specificity of E2F Activation and Repression

Various studies have detailed the role of E2F proteins in both transcription activation and repression. Further work has shown that distinct promoter elements, but comprising the same E2F recognition motif, confer positive or negative E2F control and that this reflects binding of either activator or...

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Bibliografiske detaljer
Main Authors: Freedman, Jennifer A., Chang, Jeffrey T., Jakoi, Laszlo, Nevins, Joseph R.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726897/
https://ncbi.nlm.nih.gov/pubmed/19543322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.153
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