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Specificity in the activation and control of transcription factor E2F-dependent apoptosis

Previous work has demonstrated a role for the E2F1 gene product in signaling apoptosis, both as a result of the deregulation of the Rb/E2F pathway as well as in response to DNA damage. We now show that the ability of cells to suppress the apoptotic potential of E2F1, as might occur during the course...

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Bibliografiske detaljer
Main Authors: Hallstrom, Timothy C., Nevins, Joseph R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC196891/
https://ncbi.nlm.nih.gov/pubmed/12954980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1831408100
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