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The absence of the transcription activator TFE3 impairs activation of B cells in vivo.

TFE3 is a ubiquitously expressed member of the TFE3/mi family of basic helix loop helix zipper transcription factors. TFE3 binds to muE3 sites located in the immunoglobulin heavy-chain (IgH) intronic enhancer, heavy-chain variable region promoters, the Ig kappa intronic enhancer, and regulatory site...

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Detalhes bibliográficos
Main Authors: Merrell, K, Wells, S, Henderson, A, Gorman, J, Alt, F, Stall, A, Calame, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC232186/
https://ncbi.nlm.nih.gov/pubmed/9154832
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