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Identification of a Novel E2F3 Product Suggests a Mechanism for Determining Specificity of Repression by Rb Proteins

The tumor suppressor function of Rb is intimately related to its ability to interact with E2F and repress the transcription of E2F target genes. Here we describe a novel E2F product that specifically interacts with Rb in quiescent cells. This novel E2F, which we term E2F3b, is encoded by a unique mR...

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Detalhes bibliográficos
Main Authors: Leone, Gustavo, Nuckolls, Faison, Ishida, Seiichi, Adams, Monique, Sears, Rosalie, Jakoi, Laszlo, Miron, Alexander, Nevins, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85655/
https://ncbi.nlm.nih.gov/pubmed/10779352
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