Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π-Π Stacking Stabilized Polymeric Micelles

Treatment of cancer patients with taxane-based chemotherapeutics, such as paclitaxel (PTX), is complicated by their narrow therapeutic index. Polymeric micelles are attractive nanocarriers for tumor-targeted delivery of PTX, as they can be tailored to encapsulate large amounts of hydrophobic drugs a...

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Publicat a:ACS Nano
Autors principals: Shi, Yang, van der Meel, Roy, Theek, Benjamin, Blenke, Erik Oude, Pieters, Ebel H.E., Fens, Marcel H.A.M., Ehling, Josef, Schiffelers, Raymond M., Storm, Gert, van Nostrum, Cornelus F., Lammers, Twan, Hennink, Wim E.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523313/
https://ncbi.nlm.nih.gov/pubmed/25831471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.5b00929
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