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Physico-chemical strategies to enhance stability and drug retention of polymeric micelles for tumor-targeted drug delivery

Polymeric micelles (PM) have been extensively used for tumor-targeted delivery of hydrophobic anti-cancer drugs. The lipophilic core of PM is naturally suitable for loading hydrophobic drugs and the hydrophilic shell endows them with colloidal stability and stealth properties. Decades of research on...

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Detalhes bibliográficos
Publicado no:Macromol Biosci
Main Authors: Shi, Yang, Lammers, Twan, Storm, Gert, Hennink, Wim E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410994/
https://ncbi.nlm.nih.gov/pubmed/27413999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.201600160
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