Pharmacological and Physical Vessel Modulation Strategies to Improve EPR-mediated Drug Targeting to Tumors

The performance of nanomedicine formulations depends on the Enhanced Permeability and Retention (EPR) effect. Prototypic nanomedicine-based drug delivery systems, such as liposomes, polymers and micelles, aim to exploit the EPR effect to accumulate at pathological sites, to thereby improve the balan...

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Bibliographic Details
Published in:Adv Drug Deliv Rev
Main Authors: Ojha, Tarun, Pathak, Vertika, Shi, Yang, Hennink, Wim, Moonen, Chrit, Storm, Gert, Kiessling, Fabian, Lammers, Twan
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919100/
https://ncbi.nlm.nih.gov/pubmed/28697952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2017.07.007
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