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Sonoporation enhances liposome accumulation and penetration in tumors with low EPR

The Enhanced Permeability and Retention (EPR) effect is a highly variable phenomenon. To enhance EPR-mediated passive drug targeting to tumors, several different pharmacological and physical strategies have been evaluated over the years, including e.g. TNFα-treatment, vascular normalization, hyperth...

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Bibliographic Details
Published in:J Control Release
Main Authors: Theek, Benjamin, Baues, Maike, Ojha, Tarun, Möckel, Diana, Veettil, Seena Koyadan, Steitz, Julia, van Bloois, Louis, Storm, Gert, Kiessling, Fabian, Lammers, Twan
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404719/
https://ncbi.nlm.nih.gov/pubmed/26878973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.02.021
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