Histidine-rich glycoprotein-induced vascular normalization improves EPR-mediated drug targeting to and into tumors

Tumors are characterized by leaky blood vessels, and by an abnormal and heterogeneous vascular network. These pathophysiological characteristics contribute to the enhanced permeability and retention (EPR) effect, which is one of the key rationales for developing tumor-targeted drug delivery systems....

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Control Release
Asıl Yazarlar: Theek, Benjamin, Baues, Maike, Gremse, Felix, Pola, Robert, Pechar, Michal, Jahnen-Dechent, Willi, Storm, Gert, Kiessling, Fabian, Lammers, Twan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130770/
https://ncbi.nlm.nih.gov/pubmed/29730154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.05.002
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