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Glucocorticoid-loaded core-crosslinked polymeric micelles with tailorable release kinetics for targeted rheumatoid arthritis therapy
To achieve highly effective glucocorticoid targeting for rheumatoid arthritis therapy, novel, polymerizable and hydrolytically cleavable dexamethasone (DEX) derivatives were covalently entrapped in core-crosslinked polymeric micelles. By varying the oxidation degree of the thioether in the drug link...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499037/ https://ncbi.nlm.nih.gov/pubmed/22692876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201202713 |
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