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Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π-Π Stacking Stabilized Polymeric Micelles

Treatment of cancer patients with taxane-based chemotherapeutics, such as paclitaxel (PTX), is complicated by their narrow therapeutic index. Polymeric micelles are attractive nanocarriers for tumor-targeted delivery of PTX, as they can be tailored to encapsulate large amounts of hydrophobic drugs a...

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Библиографические подробности
Опубликовано в: :ACS Nano
Главные авторы: Shi, Yang, van der Meel, Roy, Theek, Benjamin, Blenke, Erik Oude, Pieters, Ebel H.E., Fens, Marcel H.A.M., Ehling, Josef, Schiffelers, Raymond M., Storm, Gert, van Nostrum, Cornelus F., Lammers, Twan, Hennink, Wim E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523313/
https://ncbi.nlm.nih.gov/pubmed/25831471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.5b00929
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