Depletion of Foxp3(+) T Cells Abrogates Tolerance of Skin and Heart Allografts in Murine Mixed Chimeras Without the Loss of Mixed Chimerism

The relative contribution of central and peripheral mechanisms to the generation and maintenance of allograft tolerance is of considerable interest. Here, we present new evidence that regulatory T cells (Foxp3(+)) maintain skin and heart allograft tolerance in mixed hematopoietic chimeric mice. Tran...

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Detaylı Bibliyografya
Yayımlandı:Am J Transplant
Asıl Yazarlar: Shinoda, K., Akiyoshi, T., Chase, C. M., Farkash, E. A., Ndishabandi, D. K., Raczek, C. M., Sebastian, D. P., Pelle, P. Della, Russell, P. S., Madsen, J. C., Colvin, R. B., Alessandrini, A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523231/
https://ncbi.nlm.nih.gov/pubmed/25155089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12851
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