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Depletion of Foxp3(+) T Cells Abrogates Tolerance of Skin and Heart Allografts in Murine Mixed Chimeras Without the Loss of Mixed Chimerism
The relative contribution of central and peripheral mechanisms to the generation and maintenance of allograft tolerance is of considerable interest. Here, we present new evidence that regulatory T cells (Foxp3(+)) maintain skin and heart allograft tolerance in mixed hematopoietic chimeric mice. Tran...
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| Publicado no: | Am J Transplant |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4523231/ https://ncbi.nlm.nih.gov/pubmed/25155089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12851 |
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