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Depletion of Foxp3(+) T Cells Abrogates Tolerance of Skin and Heart Allografts in Murine Mixed Chimeras Without the Loss of Mixed Chimerism
The relative contribution of central and peripheral mechanisms to the generation and maintenance of allograft tolerance is of considerable interest. Here, we present new evidence that regulatory T cells (Foxp3(+)) maintain skin and heart allograft tolerance in mixed hematopoietic chimeric mice. Tran...
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| 出版年: | Am J Transplant |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4523231/ https://ncbi.nlm.nih.gov/pubmed/25155089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12851 |
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