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V(D)J recombinase induction in splenic B lymphocytes is inhibited by antigen-receptor signalling

In lymphocytes, DNA recombinations that generate the antigen-receptor genes can sometimes be reinduced in receptor-bearing cells in a process called receptor editing, which modifies the specificity of the receptor for antigen. In immature B lymphocytes, B-cell antigen receptor (BCR) signalling stimu...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Hertz, Marc, Kouskoff, Valérie, Nakamura, Tetsuya, Nemazee, David
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523147/
https://ncbi.nlm.nih.gov/pubmed/9685161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/28419
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