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Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase.

Lineage specificity and temporal ordering of immunoglobulin (Ig) and T-cell receptor (TCR) gene rearrangement are reflected in the accessibility of recombination signal sequences (RSSs) within chromatin to in vitro cleavage by the V(D)J recombinase. In this report, we investigated the basis of this...

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Detalhes bibliográficos
Main Authors: Golding, A, Chandler, S, Ballestar, E, Wolffe, A P, Schlissel, M S
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171448/
https://ncbi.nlm.nih.gov/pubmed/10393186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.13.3712
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