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Targeted Transposition by the V(D)J Recombinase

Cleavage by the V(D)J recombinase at a pair of recombination signal sequences creates two coding ends and two signal ends. The RAG proteins can integrate these signal ends, without sequence specificity, into an unrelated target DNA molecule. Here we demonstrate that such transposition events are gre...

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Detalhes bibliográficos
Main Authors: Lee, Gregory S., Neiditch, Matthew B., Sinden, Richard R., Roth, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133684/
https://ncbi.nlm.nih.gov/pubmed/11884595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.2068-2077.2002
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