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Targeted Transposition by the V(D)J Recombinase

Cleavage by the V(D)J recombinase at a pair of recombination signal sequences creates two coding ends and two signal ends. The RAG proteins can integrate these signal ends, without sequence specificity, into an unrelated target DNA molecule. Here we demonstrate that such transposition events are gre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Gregory S., Neiditch, Matthew B., Sinden, Richard R., Roth, David B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133684/
https://ncbi.nlm.nih.gov/pubmed/11884595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.2068-2077.2002
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