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Self-priming determines high type I IFN production by plasmacytoid dendritic cells
Plasmacytoid dendritic cells (pDCs) are responsible for the robust and immediate production of type I IFNs during viral infection. pDCs employ TLR7 and TLR9 to detect RNA and CpG motifs present in microbial genomes. CpG-A was the first synthetic stimulus available that induced large amounts of IFN-α...
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| Publicado en: | Eur J Immunol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4523003/ https://ncbi.nlm.nih.gov/pubmed/24338737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343806 |
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