Inhibition of Toll-Like Receptor 7- and 9-Mediated Alpha/Beta Interferon Production in Human Plasmacytoid Dendritic Cells by Respiratory Syncytial Virus and Measles Virus

Human plasmacytoid dendritic cells (PDC) are key sentinels alerting both innate and adaptive immune responses through production of huge amounts of alpha/beta interferon (IFN). IFN induction in PDC is triggered by outside-in signal transduction pathways through Toll-like receptor 7 (TLR7) and TLR9 a...

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Hlavní autoři: Schlender, Jörg, Hornung, Veit, Finke, Stefan, Günthner-Biller, Margit, Marozin, Sabrina, Brzózka, Krzysztof, Moghim, Sharareh, Endres, Stefan, Hartmann, Gunther, Conzelmann, Karl-Klaus
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1082779/
https://ncbi.nlm.nih.gov/pubmed/15827165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.9.5507-5515.2005
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