Inhibition of Toll-Like Receptor 7- and 9-Mediated Alpha/Beta Interferon Production in Human Plasmacytoid Dendritic Cells by Respiratory Syncytial Virus and Measles Virus

Human plasmacytoid dendritic cells (PDC) are key sentinels alerting both innate and adaptive immune responses through production of huge amounts of alpha/beta interferon (IFN). IFN induction in PDC is triggered by outside-in signal transduction pathways through Toll-like receptor 7 (TLR7) and TLR9 a...

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Detalhes bibliográficos
Main Authors: Schlender, Jörg, Hornung, Veit, Finke, Stefan, Günthner-Biller, Margit, Marozin, Sabrina, Brzózka, Krzysztof, Moghim, Sharareh, Endres, Stefan, Hartmann, Gunther, Conzelmann, Karl-Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1082779/
https://ncbi.nlm.nih.gov/pubmed/15827165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.9.5507-5515.2005
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