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Regulatory T-Cell Development in the Human Thymus
The thymus generates a lineage-committed subset of regulatory T-cells (Tregs), best identified by the expression of the transcription factor FOXP3. The development of thymus-derived Tregs is known to require high-avidity interaction with MHC-self peptides leading to the generation of self-reactive T...
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| Veröffentlicht in: | Front Immunol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4522873/ https://ncbi.nlm.nih.gov/pubmed/26284077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00395 |
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