Human naïve regulatory T-cells feature high steady-state turnover and are maintained by IL-7

Naïve FoxP3-expressing regulatory T-cells (Tregs) are essential to control immune responses via continuous replenishment of the activated-Treg pool with thymus-committed suppressor cells. The mechanisms underlying naïve-Treg maintenance throughout life in face of the age-associated thymic involution...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Silva, Susana L., Albuquerque, Adriana S., Serra-Caetano, Ana, Foxall, Russell B., Pires, Ana R., Matoso, Paula, Fernandes, Susana M., Ferreira, João, Cheynier, Rémi, Victorino, Rui M. M., Caramalho, Iris, Barata, João T., Sousa, Ana E.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper: Immunology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914276/
https://ncbi.nlm.nih.gov/pubmed/26910841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7512
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