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Human naïve regulatory T-cells feature high steady-state turnover and are maintained by IL-7
Naïve FoxP3-expressing regulatory T-cells (Tregs) are essential to control immune responses via continuous replenishment of the activated-Treg pool with thymus-committed suppressor cells. The mechanisms underlying naïve-Treg maintenance throughout life in face of the age-associated thymic involution...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4914276/ https://ncbi.nlm.nih.gov/pubmed/26910841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7512 |
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