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IL-7-Induced Proliferation of Human Naive CD4 T-Cells Relies on Continued Thymic Activity
Naive CD4 T-cell maintenance is critical for immune competence. We investigated here the fine-tuning of homeostatic mechanisms of the naive compartment to counteract the loss of de novo CD4 T-cell generation. Adults thymectomized in early childhood during corrective cardiac surgery were grouped base...
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| Pubblicato in: | Front Immunol |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5243809/ https://ncbi.nlm.nih.gov/pubmed/28154568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00020 |
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