Major CD4 T-Cell Depletion and Immune Senescence in a Patient with Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) results from primary defects in phagocytic reactive oxygen species (ROS) production. T-cell evaluation is usually neglected during patients’ follow-up, although T-cell depletion has been reported in CGD through unknown mechanisms. We describe here a 36-year-old pa...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Albuquerque, Adriana S., Fernandes, Susana M., Tendeiro, Rita, Cheynier, Rémi, Lucas, Margarida, Silva, Susana L., Victorino, Rui M. M., Sousa, Ana E.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425576/
https://ncbi.nlm.nih.gov/pubmed/28553289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00543
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