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Brief review: Regulatory T cell development in the thymus

Development of a comprehensive regulatory T cell compartment in the thymus is required to maintain immune homeostasis and prevent autoimmunity. Here, we review cellular and molecular determinants of T(reg) cell development in the thymus. We focus on the evidence for a self-antigen focused T(reg) cel...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Owen, David L., Sjaastad, Louisa E., Farrar, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910132/
https://ncbi.nlm.nih.gov/pubmed/31591259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900662
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