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Preemptive Genotyping of CYP2C8 and CYP2C9 Allelic Variants Involved in NSAIDs Metabolism for Sickle Cell Disease Pain Management

Interindividual variability in analgesic effects of nonsteroidal anti‐inflammatory drugs prescribed for sickle cell disease (SCD) pain is attributed to polymorphisms in the CYP2C8 and CYP2C9 enzymes. We described CYP2C8 and CYP2C9 genotype/phenotype profiles and frequency of emergency department (ED...

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Dades bibliogràfiques
Publicat a:Clin Transl Sci
Autors principals: Jaja, Cheedy, Bowman, Latanya, Wells, Leigh, Patel, Niren, Xu, Hongyan, Lyon, Matt, Kutlar, Abdullah
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522406/
https://ncbi.nlm.nih.gov/pubmed/25640739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12260
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