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The influence of the CYP2C19*10 allele on clopidogrel activation and CYP2C19*2 genotyping
The polymorphic hepatic enzyme CYP2C19 catalyzes the metabolism of clinically important drugs such as clopidogrel, proton-pump inhibitors, and others and clinical pharmacogenetic testing for clopidogrel is increasingly common. The CYP2C19*10 SNP is located 1 bp upstream the CYP2C19*2 SNP. Despite th...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4090277/ https://ncbi.nlm.nih.gov/pubmed/24945780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000068 |
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