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Preemptive Genotyping of CYP2C8 and CYP2C9 Allelic Variants Involved in NSAIDs Metabolism for Sickle Cell Disease Pain Management

Interindividual variability in analgesic effects of nonsteroidal anti‐inflammatory drugs prescribed for sickle cell disease (SCD) pain is attributed to polymorphisms in the CYP2C8 and CYP2C9 enzymes. We described CYP2C8 and CYP2C9 genotype/phenotype profiles and frequency of emergency department (ED...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Jaja, Cheedy, Bowman, Latanya, Wells, Leigh, Patel, Niren, Xu, Hongyan, Lyon, Matt, Kutlar, Abdullah
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522406/
https://ncbi.nlm.nih.gov/pubmed/25640739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12260
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