Preemptive Genotyping of CYP2C8 and CYP2C9 Allelic Variants Involved in NSAIDs Metabolism for Sickle Cell Disease Pain Management

Interindividual variability in analgesic effects of nonsteroidal anti‐inflammatory drugs prescribed for sickle cell disease (SCD) pain is attributed to polymorphisms in the CYP2C8 and CYP2C9 enzymes. We described CYP2C8 and CYP2C9 genotype/phenotype profiles and frequency of emergency department (ED...

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Bibliographic Details
Published in:Clin Transl Sci
Main Authors: Jaja, Cheedy, Bowman, Latanya, Wells, Leigh, Patel, Niren, Xu, Hongyan, Lyon, Matt, Kutlar, Abdullah
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
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Original Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522406/
https://ncbi.nlm.nih.gov/pubmed/25640739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12260
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