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Membrane-Active Sequences within gp41 Membrane Proximal External Region (MPER) Modulate MPER-Containing Peptidyl Fusion Inhibitor Activity and the Biosynthesis of HIV-1 Structural Proteins

The membrane proximal external region (MPER) is a highly conserved membrane-active region located at the juxtamembrane positions within class I viral fusion glycoproteins and essential for membrane fusion events during viral entry. The MPER in the human immunodeficiency virus type I (HIV-1) envelope...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhang, Si Min, Jejcic, Alenka, Tam, James P., Vahlne, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521866/
https://ncbi.nlm.nih.gov/pubmed/26230322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134851
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