Immunogenicity of Membrane-bound HIV-1 gp41 Membrane-proximal External Region (MPER) Segments Is Dominated by Residue Accessibility and Modulated by Stereochemistry

Structural characterization of epitope-paratope pairs has contributed to the understanding of antigenicity. By contrast, few structural studies relate to immunogenicity, the process of antigen-induced immune responses in vivo. Using a lipid-arrayed membrane-proximal external region (MPER) of HIV-1 g...

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Detalhes bibliográficos
Main Authors: Kim, Mikyung, Song, Likai, Moon, James, Sun, Zhen-Yu J., Bershteyn, Anna, Hanson, Melissa, Cain, Derek, Goka, Selasie, Kelsoe, Garnett, Wagner, Gerhard, Irvine, Darrell, Reinherz, Ellis L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814781/
https://ncbi.nlm.nih.gov/pubmed/24047898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.494609
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