Analyzing allele specific RNA expression using mixture models

BACKGROUND: Measuring allele-specific RNA expression provides valuable insights into cis-acting genetic and epigenetic regulation of gene expression. Widespread adoption of high-throughput sequencing technologies for studying RNA expression (RNA-Seq) permits measurement of allelic RNA expression imb...

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Publicat a:BMC Genomics
Autors principals: Lu, Rong, Smith, Ryan M, Seweryn, Michal, Wang, Danxin, Hartmann, Katherine, Webb, Amy, Sadee, Wolfgang, Rempala, Grzegorz A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Methodology Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521363/
https://ncbi.nlm.nih.gov/pubmed/26231172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1749-0
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