Allele-Selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-Coding and Noncoding RNAs, and RNA Isoforms

mRNA translation into proteins is highly regulated, but the role of mRNA isoforms, noncoding RNAs (ncRNAs), and genetic variants remains poorly understood. mRNA levels on polysomes have been shown to correlate well with expressed protein levels, pointing to polysomal loading as a critical factor. To...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mascarenhas, Roshan, Pietrzak, Maciej, Smith, Ryan M., Webb, Amy, Wang, Danxin, Papp, Audrey C., Pinsonneault, Julia K., Seweryn, Michal, Rempala, Grzegorz, Sadee, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558023/
https://ncbi.nlm.nih.gov/pubmed/26331722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136798
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