Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex

The transcriptional response to infection with the bacterium Listeria monocytogenes (Lm) requires cooperative signals of the type I interferon (IFN-I)-stimulated JAK-STAT and proinflammatory NF-κB pathways. Using ChIP-seq analysis, we define genes induced in Lm-infected macrophages through synergist...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Wienerroither, Sebastian, Shukla, Priyank, Farlik, Matthias, Majoros, Andrea, Stych, Bernadette, Vogl, Claus, Cheon, HyeonJoo, Stark, George R., Strobl, Birgit, Müller, Mathias, Decker, Thomas
Format: Artigo
Langue:Inglês
Publié: Cell Press 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521078/
https://ncbi.nlm.nih.gov/pubmed/26146080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.021
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