Antimicrobial Peptide Resistance of Vibrio cholerae Results from an LPS Modification Pathway Related to Nonribosomal Peptide Synthetases

[Image: see text] The current pandemic El Tor biotype of O1 Vibrio cholerae is resistant to polymyxins, whereas the previous pandemic strain of the classical biotype is polymyxin sensitive. The almEFG operon found in El Tor V. cholerae confers >100-fold resistance to polymyxins through the glycyl...

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Bibliografiset tiedot
Julkaisussa:ACS Chem Biol
Päätekijät: Henderson, Jeremy C., Fage, Christopher D., Cannon, Joe R., Brodbelt, Jennifer S., Keatinge-Clay, Adrian T., Trent, M. Stephen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2014
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520716/
https://ncbi.nlm.nih.gov/pubmed/25068415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500438x
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