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Antimicrobial Peptide Resistance of Vibrio cholerae Results from an LPS Modification Pathway Related to Nonribosomal Peptide Synthetases

[Image: see text] The current pandemic El Tor biotype of O1 Vibrio cholerae is resistant to polymyxins, whereas the previous pandemic strain of the classical biotype is polymyxin sensitive. The almEFG operon found in El Tor V. cholerae confers >100-fold resistance to polymyxins through the glycyl...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Henderson, Jeremy C., Fage, Christopher D., Cannon, Joe R., Brodbelt, Jennifer S., Keatinge-Clay, Adrian T., Trent, M. Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520716/
https://ncbi.nlm.nih.gov/pubmed/25068415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500438x
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