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Antimicrobial Peptide Resistance of Vibrio cholerae Results from an LPS Modification Pathway Related to Nonribosomal Peptide Synthetases

[Image: see text] The current pandemic El Tor biotype of O1 Vibrio cholerae is resistant to polymyxins, whereas the previous pandemic strain of the classical biotype is polymyxin sensitive. The almEFG operon found in El Tor V. cholerae confers >100-fold resistance to polymyxins through the glycyl...

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Bibliographische Detailangaben
Veröffentlicht in:ACS Chem Biol
Hauptverfasser: Henderson, Jeremy C., Fage, Christopher D., Cannon, Joe R., Brodbelt, Jennifer S., Keatinge-Clay, Adrian T., Trent, M. Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520716/
https://ncbi.nlm.nih.gov/pubmed/25068415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500438x
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