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The Effect of WNK4 on the Na(+)–Cl(−) Cotransporter Is Modulated by Intracellular Chloride
It is widely recognized that the phenotype of familial hyperkalemic hypertension is mainly a consequence of increased activity of the renal Na(+)–Cl(−) cotransporter (NCC) because of altered regulation by with no–lysine–kinase 1 (WNK1) or WNK4. The effect of WNK4 on NCC, however, has been controvers...
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| Published in: | J Am Soc Nephrol |
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| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society of Nephrology
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4520168/ https://ncbi.nlm.nih.gov/pubmed/25542968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014050470 |
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