A DNA binding motif coordinating synthesis and degradation in proofreading DNA polymerases.

The functional significance of the conserved motif 'YxGG/A', located between the 3'-5' exonuclease and polymerization domains of eukaryotic-type DNA polymerases, has been studied by site-directed mutagenesis in phi29 DNA polymerase. Single substitutions at this region were obtain...

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Bibliographische Detailangaben
Hauptverfasser: Truniger, V, Lázaro, J M, Salas, M, Blanco, L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC451907/
https://ncbi.nlm.nih.gov/pubmed/8670845
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