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Involvement of φ29 DNA polymerase thumb subdomain in the proper coordination of synthesis and degradation during DNA replication

φ29 DNA polymerase achieves a functional coupling between its 3′–5′ exonuclease and polymerization activities by means of important contacts with the DNA at both active sites. The placement and orientation of residues Lys538, Lys555, Lys557, Gln560, Thr571, Thr573 and Lys575 in a modelled φ29 DNA po...

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Detaylı Bibliyografya
Asıl Yazarlar: Pérez-Arnaiz, Patricia, Lázaro, José M., Salas, Margarita, de Vega, Miguel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1475753/
https://ncbi.nlm.nih.gov/pubmed/16757576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl402
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