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New insights into the coordination between the polymerization and 3′-5′ exonuclease activities in ϕ29 DNA polymerase
Bacteriophage ϕ29 DNA polymerase has two activities: DNA polymerization and 3′-5′ exonucleolysis governed by catalytic sites present in two structurally distant domains. These domains must work together to allow the correct replication of the template and to prevent the accumulation of errors in the...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6351526/ https://ncbi.nlm.nih.gov/pubmed/30696917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37513-7 |
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