A carregar...
Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1 self-limitation
Osteoclasts are bone-resorbing cells essential for skeletal remodeling. However, over-active osteoclasts can cause bone-degenerative disorders. Therefore, the level of NFATc1, the master transcription factor of osteoclast, must be tightly controlled. Although the activation and amplification of NFAT...
Na minha lista:
| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4518709/ https://ncbi.nlm.nih.gov/pubmed/26173181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07217 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|