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HDAC9 Inhibits Osteoclastogenesis via Mutual Suppression of PPARγ/RANKL Signaling

Recent studies suggest that the class II histone deacetylase (HDAC)9 plays important roles in physiology such as metabolism and immunity. Here, we report that HDAC9 also controls bone turnover by suppressing osteoclast differentiation and bone resorption. HDAC9 expression is down-regulated during os...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Jin, Zixue, Wei, Wei, Huynh, HoangDinh, Wan, Yihong
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415206/
https://ncbi.nlm.nih.gov/pubmed/25793404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1365
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