Voltage-gated sodium channels and cancer: is excitability their primary role?

Voltage-gated sodium channels (Na(V)) are molecular characteristics of excitable cells. Their activation, triggered by membrane depolarization, generates transient sodium currents that initiate action potentials in neurons and muscle cells. Sodium currents were discovered by Hodgkin and Huxley using...

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Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Roger, Sébastien, Gillet, Ludovic, Le Guennec, Jean-Yves, Besson, Pierre
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2015
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518325/
https://ncbi.nlm.nih.gov/pubmed/26283962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00152
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