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Voltage-gated sodium channels and cancer: is excitability their primary role?

Voltage-gated sodium channels (Na(V)) are molecular characteristics of excitable cells. Their activation, triggered by membrane depolarization, generates transient sodium currents that initiate action potentials in neurons and muscle cells. Sodium currents were discovered by Hodgkin and Huxley using...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Roger, Sébastien, Gillet, Ludovic, Le Guennec, Jean-Yves, Besson, Pierre
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518325/
https://ncbi.nlm.nih.gov/pubmed/26283962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00152
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