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Voltage-gated sodium channels and cancer: is excitability their primary role?
Voltage-gated sodium channels (Na(V)) are molecular characteristics of excitable cells. Their activation, triggered by membrane depolarization, generates transient sodium currents that initiate action potentials in neurons and muscle cells. Sodium currents were discovered by Hodgkin and Huxley using...
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| Pubblicato in: | Front Pharmacol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4518325/ https://ncbi.nlm.nih.gov/pubmed/26283962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00152 |
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