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Voltage-gated sodium channels and cancer: is excitability their primary role?
Voltage-gated sodium channels (Na(V)) are molecular characteristics of excitable cells. Their activation, triggered by membrane depolarization, generates transient sodium currents that initiate action potentials in neurons and muscle cells. Sodium currents were discovered by Hodgkin and Huxley using...
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| Publié dans: | Front Pharmacol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4518325/ https://ncbi.nlm.nih.gov/pubmed/26283962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00152 |
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