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Voltage-gated sodium channels and cancer: is excitability their primary role?

Voltage-gated sodium channels (Na(V)) are molecular characteristics of excitable cells. Their activation, triggered by membrane depolarization, generates transient sodium currents that initiate action potentials in neurons and muscle cells. Sodium currents were discovered by Hodgkin and Huxley using...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Pharmacol
Prif Awduron: Roger, Sébastien, Gillet, Ludovic, Le Guennec, Jean-Yves, Besson, Pierre
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518325/
https://ncbi.nlm.nih.gov/pubmed/26283962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00152
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