Active suppression of intestinal CD4(+)TCRαβ(+) T-lymphocyte maturation during the postnatal period

Priming of the mucosal immune system during the postnatal period substantially influences host–microbial interaction and susceptibility to immune-mediated diseases in adult life. The underlying mechanisms are ill defined. Here we show that shortly after birth, CD4 T cells populate preformed lymphoid...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Torow, Natalia, Yu, Kai, Hassani, Kasra, Freitag, Jenny, Schulz, Olga, Basic, Marijana, Brennecke, Anne, Sparwasser, Tim, Wagner, Norbert, Bleich, André, Lochner, Matthias, Weiss, Siegfried, Förster, Reinhold, Pabst, Oliver, Hornef, Mathias W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518322/
https://ncbi.nlm.nih.gov/pubmed/26195040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8725
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