Evidence for a functional sidedness to the αβTCR

The T cell receptor (TCR) and associated CD3γε, δε, and ζζ signaling dimers allow T cells to discriminate between different antigens and respond accordingly, but our knowledge of how these parts fit and work together is incomplete. In this study, we provide additional evidence that the CD3 heterodim...

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Bibliografiske detaljer
Main Authors: Kuhns, Michael S., Girvin, Andrew T., Klein, Lawrence O., Chen, Rebecca, Jensen, Kirk D.C., Newell, Evan W., Huppa, Johannes B., Lillemeier, Björn F., Huse, Morgan, Chien, Yueh-hsiu, Garcia, K. Christopher, Davis, Mark M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841884/
https://ncbi.nlm.nih.gov/pubmed/20202921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000925107
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